COLLAGEN FOR U.I. MINIMAL DOSE INJECTIONS IN SCHEDULED STEPS TO IMPROVE CLINICAL RESULTS

Abstract

Endoscopic treatment of urinary incontinence is based on the use of injectables. We use collagen (Contigen-Bard) to make the bladder neck narrower in order to ensure dynamic continence and avoid obstruction. Gax collagen is highly purified, hardly viscous bovine dermal collagen, cross-linked with glutaraldehyde in saline solution. The possible approaches for the endoscopic collagen implant are: perineal, paraurethral and transurethral, which is our choice. We are in favour of repeated injections in scheduled steps with a minimal dose: 5 ml injected transurethrally in the positions 5 and 7 every 2 months, three times: 24 patients (18 women and 6 men) average age 58, underwent the treatment and were checked with a twelve months follow-up. Effectiveness was complete in 12 women and 3 men, a significant improvement of the quality of life was reported in the other patients.